Michael J. Mitchell

Hibbert Professor

Bioengineering

Research

The Mitchell lab’s research broadly lies at the interface of biomaterials science, drug delivery, and cellular and molecular bioengineering to fundamentally understand and therapeutically target biological barriers. Specifically, his lab engineers new lipid and polymeric nanoparticle platforms for the delivery of different nucleic acid modalities to target cells and tissues across the body. His lab applies their research findings and the technologies developed to a range of human health applications, including the engineering of CAR T cells for cancer immunotherapy, mRNA vaccines, genome editing, cardiovascular disease, and in utero therapeutics to treat disease before birth.

Education

He received a BE in Biomedical Engineering from Stevens Institute of Technology in 2009, a PhD in Biomedical Engineering with Prof. Michael King from Cornell University in 2014. He was a Postdoctoral Fellow in Chemical Engineering with Prof. Robert Langer at MIT from 2014-2017, prior to pursuing his independent career at University of Pennsylvania in 2018.

 

B.E. Biomedical Engineering, Stevens Institute of Technology, 2009

M.E. Materials Science and Engineering, Stevens Institute of Technology, 2009

M.S. Biomedical Engineering, Cornell University, 2012

Ph.D. Biomedical Engineering, Cornell University, 2014

Awards

2014-2017 NIH NCI Ruth L. Kirschstein Postdoctoral Fellowship (F32), National Cancer Institute

2017 Burroughs Wellcome Fund Career Award at the Scientific Interface

2018 National Institutes of Health Director’s New Innovator Award

2019 Controlled Release Society T. Nagai Award

2021 Emerging Inventor of the Year, Penn Center for Innovation

2022 National Science Foundation CAREER Award

2022 Society for Biomaterials Young Investigator Award

2023 Cellular and Molecular Bioengineering Young Innovator Award